Нутрициология с учетом нейроразнообразия: Оценка системы NutriSteppe-AI в управлении диетическими ограничениями и метаболическим синдромом при аутизме
DOI:
https://doi.org/10.53498/rw6jqz83Ключевые слова:
расстройство аутистического спектра, пищевые ограничения, избирательность в еде, скрытая недостаточность питания, метаболический синдром, нейроразнообразие, цифровое здравоохранение, искусственный интеллект, поддержка лиц, осуществляющих уход, Центральная АзияАннотация
Лица с расстройством аутистического спектра (РАС) сталкиваются с особой и клинически недооцениваемой формой пищевых ограничений, обусловленной не предпочтениями, а нейроонтогенетическими особенностями состояния — нарушением сенсорной фильтрации, когнитивной ригидностью и дисфункцией интероцепции. Возникающее сужение пищевого рациона, нередко до менее чем двадцати преимущественно ультрапереработанных продуктов, формирует картину скрытой недостаточности питания, которая на протяжении жизни каскадно приводит к дисбиозу кишечника, хроническому воспалению, метаболическому синдрому и повышенному риску неинфекционных заболеваний. Стандартное диетологическое консультирование и распространенные цифровые инструменты для здоровья, ориентированные на нейротипичного пользователя, для этой группы зачастую недоступны или прямо вредны, а рекомендуемая доказательной медициной междисциплинарная специализированная помощь структурно недоступна большинству семей, особенно в странах Центральной Азии и постсоветского пространства.
В настоящем нарративном обзоре обобщаются современные данные о нейроонтогенетических истоках пищевых ограничений при РАС и их прогрессировании в сторону метаболических заболеваний, а также рассматриваются концептуальные основы и клиническая архитектура системы NutriSteppe-AI — цифровой системы питания, учитывающей нейроразнообразие.
Описываются разделение детерминированных нутрициологических расчетов и коммуникации на основе языковой модели, пять последовательных уровней сенсорной безопасности, функции формирования навыков у лиц, осуществляющих уход, и культурно адаптированная база данных продуктов Центральной Азии как механизмы обеспечения безопасной, непрерывной и персонализированной нутритивной поддержки без опоры на дефицитные команды специалистов. Для оценки клинической эффективности в Алматы проводится 12-недельное рандомизированное контролируемое исследование.
Библиографические ссылки
1. Maenner, M. J., Warren, Z., Williams, A. R., Amoakohene, E., Bakian, A. V., Bilder, D. A., Durkin, M. S., Fitzgerald, R. T., Furnier, S. M., Hughes, M. M., Ladd-Acosta, C. M., McArthur, D., Pas, E. T., Salinas, A., Vehorn, A., Williams, S., Esler, A., Grzybowski, A., Hall-Lande, J., Nguyen, R. H. N., … Shaw, K. A. (2023). Prevalence and characteristics of autism spectrum disorder among children aged 8 years—Autism and Developmental Disabilities Monitoring Network, 11 sites, United States, 2020. MMWR Surveillance Summaries, 72(2), 1–14. https://doi.org/10.15585/mmwr.ss7202a1
2. Autism Speaks. Autism Statistics and Facts. Website. [Cited 01 Feb 2026]. Available from URL: https://www.autismspeaks.org/autism-statistics-asd
3. Bandini, L. G., Anderson, S. E., Curtin, C., Cermak, S., Evans, E. W., Scampini, R., Maslin, M., & Must, A. (2010). Food selectivity in children with autism spectrum disorders and typically developing children. Journal of Pediatrics, 157(2), 259–264. https://doi.org/10.1016/j.jpeds.2010.02.013
4. Sharp, W. G., Berry, R. C., McCracken, C., Nuhu, N. N., Marvel, E., Saulnier, C. A., Klin, A., Jones, W., & Jaquess, D. L. (2013). Feeding problems and nutrient intake in children with autism spectrum disorders: A meta-analysis and comprehensive review of the literature. Journal of Autism and Developmental Disorders, 43(9), 2159–2173. https://doi.org/10.1007/s10803-013-1771-
5. Kahathuduwa, C. N., West, B. D., Blume, J., Dharavath, N., Moustaid-Moussa, N., & Mastergeorge, A. (2019). The risk of overweight and obesity in children with autism spectrum disorders: A systematic review and meta-analysis. Obesity Reviews, 20(12), 1667–1679. https://doi.org/10.1111/obr.12933
6. Chieh, A. Y., Bryant, B. M., Kim, J. W., & Li, L. (2021). Systematic review investigating the relationship between autism spectrum disorder and metabolic dysfunction. Research in Autism Spectrum Disorders, 86, 101821. https://doi.org/10.1016/j.rasd.2021.101821
7. Fattorusso, A., Di Genova, L., Dell’Isola, G. B., Mencaroni, E., & Esposito, S. (2019). Autism spectrum disorders and the gut microbiota. Nutrients, 11(3), 521. https://doi.org/10.3390/nu11030521
8. Tomaszek, N., Urbaniak, A. D., Bałdyga, D., Chwesiuk, K., Modzelewski, S., & Waszkiewicz, N. (2025). Unraveling the connections: eating issues, microbiome, and gastrointestinal symptoms in autism spectrum disorder. Nutrients, 17(3), 486. https://doi.org/10.3390/nu17030486
9. Önal, S., Sachadyn-Król, M., & Kostecka, M. (2023). A review of the nutritional approach and the role of dietary components in children with autism spectrum disorders in light of the latest scientific research. Nutrients, 15(23), 4852. https://doi.org/10.3390/nu15234852
10. Castro, K., Faccioli, L. S., Baronio, D., Gottfried, C., Perry, I. S., & Riesgo, R. (2016). Feeding behavior and dietary intake of male children and adolescents with autism spectrum disorder: A case-control study. International Journal of Developmental Neuroscience 3, 68-74. https://doi.org/10.1016/j.ijdevneu.2016.07.003
11. Cermak, S. A., Curtin, C., & Bandini, L. G. (2010). Food selectivity and sensory sensitivity in children with autism spectrum disorders. Journal of the American dietetic Association, 110(2), 238-246. https://doi.org/10.1016/j.jada.2009.10.032
12. Schreck, K. A., Williams, K., & Smith, A. F. (2004). A comparison of eating behaviors between children with and without autism. Journal of autism and developmental disorders, 34(4), 433-438. https://doi.org/10.1023/B:JADD.0000037419.78531.86
13. Williams, P. G., Dalrymple, N., & Neal, J. (2000). Eating habits of children with autism. Pediatric Nursing, 26(3), 259–264. https://doi.org/10.0.0/placeholder
14. Schmitt, L., Heiss, C. J., & Campbell, E. E. (2008). A comparison of nutrient intake and eating behaviors of boys with and without autism. Topics in clinical nutrition, 23(1), 23-31. https://doi.org/10.1097/01.TIN.0000312077.45953.6c
15. Marco, E. J., Hinkley, L. B., Hill, S. S., & Nagarajan, S. S. (2011). Sensory processing in autism: a review of neurophysiologic findings. Pediatric research, 69(8), 48-54. https://doi.org/10.1203/PDR.0b013e3182130b54
16. Lord, C., Elsabbagh, M., Baird, G., & Veenstra-Vanderweele, J. (2018). Autism spectrum disorder. The lancet, 392(10146), 508-520. https://doi.org/10.1016/S0140-6736(18)31129-2
17. Ben-Sasson, A., Hen, L., Fluss, R., Cermak, S. A., Engel-Yeger, B., & Gal, E. (2009). A meta-analysis of sensory modulation symptoms in individuals with autism spectrum disorders. Journal of autism and developmental disorders, 39(1), 1-11. https://doi.org/10.1007/s10803-008-0593-3
18. Green, S. A., Ben-Sasson, A., Soto, T. W., & Carter, A. S. (2012). Anxiety and sensory over-responsivity in toddlers with autism spectrum disorders: Bidirectional effects across time. Journal of autism and developmental disorders, 42(6), 1112-1119. https://doi.org/10.1007/s10803-011-1361-3
19. Nadon, G., Feldman, D. E., Dunn, W., & Gisel, E. (2011). Association of sensory processing and eating problems in children with autism spectrum disorders. Autism research and treatment, 2011(1), 541926. https://doi.org/10.1155/2011/541926
20. Rozenkrantz, L., Zachor, D., Heller, I., Plotkin, A., Weissbrod, A., Snitz, K., Secundo, L., & Sobel, N. (2015). A mechanistic link between olfaction and autism spectrum disorder. Current Biology, 25(14), 1904–1910. https://doi.org/10.1016/j.cub.2015.05.048
21. Scheier, Z. A., Sturm, K. L., Colavecchio, J. A., Pradhan, A., & Otazu, G. H. (2024). Role of odor novelty on olfactory issues in autism spectrum disorder. Genes, Brain and Behavior, 23(6), e70008. https://doi.org/10.1111/gbb.70008
22. Ashwin, C., Chapman, E., Howells, J., Rhydderch, D., Walker, I., & Baron-Cohen, S. (2014). Enhanced olfactory sensitivity in autism spectrum conditions. Molecular Autism, 5(1), 53. https://doi.org/10.1186/2040-2392-5-53
23. Larsson, M., Tirado, C., & Wiens, S. (2017). A meta-analysis of odor thresholds and odor identification in autism spectrum disorders. Frontiers in psychology, 8, 679. https://doi.org/10.3389/fpsyg.2017.00679
24. Goday, P. S., Huh, S. Y., Silverman, A., Lukens, C. T., Dodrill, P., Cohen, S. S., Delaney, A. L., Feuling, M. B., Noel, R. J., Gisel, E., Kenzer, A., Kessler, D. B., Kraus de Camargo, O., Browne, J., & Phalen, J. A. (2019). Pediatric feeding disorder: Consensus definition and conceptual framework. Journal of Pediatric Gastroenterology and Nutrition, 68(1), 124–129. https://doi.org/10.1097/MPG.0000000000002188
25. Hill, E. L. (2004). Executive dysfunction in autism. Trends in cognitive sciences, 8(1), 26-32. https://doi.org/10.1016/j.tics.2003.11.003
26. Curtin, C., Hubbard, K., Anderson, S. E., Mick, E., Must, A., & Bandini, L. G. (2015). Food selectivity, mealtime behavior problems, spousal stress, and family food choices in children with and without autism spectrum disorder. Journal of autism and developmental disorders, 45(10), 3308-3315. https://doi.org/10.1007/s10803-015-2490-x
27. Lord, C., Brugha, T. S., Charman, T., Cusack, J., Dumas, G., Frazier, T., Jones, E. J. H., Jones, R. M., Pickles, A., State, M. W., Taylor, J. L., & Veenstra-VanderWeele, J. (2020). Autism spectrum disorder. Nature Reviews Disease Primers, 6(1), 5. https://doi.org/10.1038/s41572-019-0138-4
28. Mosconi, M. W., Mohanty, S., Greene, R. K., Cook, E. H., Vaillancourt, D. E., & Sweeney, J. A. (2015). Feedforward and feedback motor control abnormalities implicate cerebellar dysfunctions in autism spectrum disorder. Journal of Neuroscience, 35(5). https://doi.org/10.1523/JNEUROSCI.2731-14.2015
29. Kodak, T., & Piazza, C. C. (2008). Assessment and behavioral treatment of feeding and sleeping disorders in children with autism spectrum disorders. Child and adolescent psychiatric clinics of North America, 17(4), 887-905. https://doi.org/10.1016/j.chc.2008.06.005
30. Ledford, J. R., & Gast, D. L. (2006). Feeding problems in children with autism spectrum disorders: A review. Focus on autism and other developmental disabilities, 21(3), 153-166. https://doi.org/10.1177/10883576060210030401
31. Volkert, V. M., & Vaz, P. C. (2010). Recent studies on feeding problems in children with autism. Journal of applied behavior analysis, 43(1), 155-159. https://doi.org/10.1901/jaba.2010.43-155
32. Quattrocki, E., & Friston, K. (2014). Autism, oxytocin and interoception. Neuroscience & Biobehavioral Reviews, 47, 410-430. https://doi.org/10.1016/j.neubiorev.2014.09.012
33. Shah, P., Hall, R., Catmur, C., & Bird, G. (2016). Alexithymia, not autism, is associated with impaired interoception. Cortex, 81, 215–220. https://doi.org/10.1016/j.cortex.2016.03.021
34. Ebisch, S. J., Gallese, V., Willems, R. M., Mantini, D., Groen, W. B., Romani, G. L., Bekkering, H. (2011). Altered intrinsic functional connectivity of anterior and posterior insula regions in high‐functioning participants with autism spectrum disorder. Human Brain Mapping, 32(7), 1013–1028. https://doi.org/10.1002/hbm.21085
35. Zhou, Y., Shi, L., Cui, X., Wang, S., & Luo, X. (2016). Functional connectivity of the caudal anterior cingulate cortex is decreased in autism. PloS one, 11(3), e0151879. https://doi.org/10.1371/journal.pone.0151879
36. Preece, D., Becerra, R., Robinson, K., Dandy, J., & Allan, A. (2018). The psychometric assessment of alexithymia: Development and validation of the Perth Alexithymia Questionnaire. Personality and Individual Differences, 132, 32-44. https://doi.org/10.1016/j.paid.2018.05.011
37. Zheng, Z., Zhang, L., Li, S., Zhao, F., Wang, Y., Huang, L., Huang, J., Zou, R., Qu, Y., & Mu, D. (2017). Association among obesity, overweight and autism spectrum disorder: A systematic review and meta-analysis. Scientific Reports, 7(1), 11697. https://doi.org/10.1038/s41598-017-12003-4
38. Hyman, S. L., Stewart, P. A., Schmidt, B., Cain, U., Lemcke, N., Foley, J. T., Peck, R., Clemons, T., Reynolds, A., Johnson, C., Handen, B., James, S. J., Ng, P. K., & Courtney, P. M. (2012). Nutrient intake from food in children with autism. Pediatrics, 130(Supplement 2), S145–S153. https://doi.org/10.1542/peds.2012-0900L
39. Zimmer, M. H., Hart, L. C., Manning-Courtney, P., Murray, D. S., Bing, N. M., & Summer, S. (2012). Food variety as a predictor of nutritional status among children with autism. Journal of autism and developmental disorders, 42(4), 549-556. https://doi.org/10.1007/s10803-011-1268-z
40. Levy, S. E., Souders, M. C., Ittenbach, R. F., Giarelli, E., Mulberg, A. E., & Pinto-Martin, J. A. (2007). Relationship of dietary intake to gastrointestinal symptoms in children with autistic spectrum disorders. Biological psychiatry, 61(4), 492-497. https://doi.org/10.1016/j.biopsych.2006.07.013
41. Arija, V., Esteban-Figuerola, P., Morales-Hidalgo, P., Jardi, C., & Canals-Sans, J. (2023). Nutrient intake and adequacy in children with autism spectrum disorder: EPINED epidemiological study. Autism, 27(2), 371-388. https://doi.org/10.1177/13623613221098237
42. Gan, H., Su, Y., Zhang, L., Huang, G., Lai, C., Lv, Y., & Li, Y. (2023). Questionnaire-based analysis of autism spectrum disorders and gastrointestinal symptoms in children and adolescents: a systematic review and meta-analysis. Frontiers in Pediatrics, 11, 1120728. https://doi.org/10.3389/fped.2023.1120728
43. Holingue, C., Newill, C., Lee, L. C., Pasricha, P. J., & Daniele Fallin, M. (2018). Gastrointestinal symptoms in autism spectrum disorder: A review of the literature on ascertainment and prevalence. Autism Research, 11(1), 24-36. https://doi.org/10.1002/aur.1854
44. Molloy, C. A., & Manning-Courtney, P. (2003). Prevalence of chronic gastrointestinal symptoms in children with autism and autistic spectrum disorders. Autism, 7(2), 165-171. https://doi.org/10.1177/1362361303007002004
45. Afzal, N., Murch, S., Thirrupathy, K., Berger, L., Fagbemi, A., & Heuschkel, R. (2003). Constipation with acquired megarectum in children with autism. Pediatrics, 112(4), 939-942. https://doi.org/10.1542/peds.112.4.939
46. Buie, T., Fuchs, G. J., III, Furuta, G. T., Kooros, K., Levy, J., Lewis, J. D., Wershil, B. K., Winter, H., & the Autism Consortium Panel. (2010). Recommendations for evaluation and treatment of common gastrointestinal problems in children with ASDs. Pediatrics, 125(Supplement 1), S19–S29. https://doi.org/10.1542/peds.2009-1878D
47. Li, Q., Han, Y., Dy, A. B. C., & Hagerman, R. J. (2017). The gut microbiota and autism spectrum disorders. Frontiers in cellular neuroscience, 11, 120. https://doi.org/10.3389/fncel.2017.00120
48. Cryan, J. F., O’Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., Guzzetta, K. E., Jaggar, M., Long-Smith, C. M., Lyte, J. M., Martin, J. A., Molinero-Perez, A., Moloney, G. M., Morelli, E., Morillas, E., … Dinan, T. G. (2019). The microbiota–gut–brain axis. Physiological Reviews, 99(4), 1877–2013. https://doi.org/10.1152/physrev.00018.2018
49. Frye, R. E., Rose, S., Slattery, J., & MacFabe, D. F. (2015). Gastrointestinal dysfunction in autism spectrum disorder: the role of the mitochondria and the enteric microbiome. Microbial ecology in health and disease, 26(1), 27458. https://doi.org/10.3402/mehd.v26.27458
50. Hyman, S. L., Stewart, P. A., Schmidt, B., Cain, U., Lemcke, N., Foley, J. T., Peck, R., Clemons, T., Reynolds, A., Johnson, C., Handen, B., James, S. J., Ng, P. K., & Courtney, P. M. (2012). Nutrient intake from food in children with autism. Pediatrics, 130(Supplement 2), S145–S153. https://doi.org/10.1542/peds.2012-0900L
51. Neumeyer, A. M., Gates, A., Ferrone, C., Lee, H., & Misra, M. (2013). Bone density in peripubertal boys with autism spectrum disorders. Journal of autism and developmental disorders, 43(7), 1623-1629. https://doi.org/10.1007/s10803-012-1709-3
52. Al-Beltagi, M. (2024). Nutritional management and autism spectrum disorder: A systematic review. World Journal of Clinical Pediatrics, 13(4), 99649. https://doi.org/10.5409/wjcp.v13.i4.99649
53. Guo, M., Zhu, J., Yang, T., Lai, X., Lei, Y., Chen, J., & Li, T. (2019). Vitamin A and vitamin D deficiencies exacerbate symptoms in children with autism spectrum disorders. Nutritional neuroscience, 22(9), 637-647.https://doi.org/10.1080/1028415X.2018.1432558
54. Mazahery, H., Camargo Jr, C. A., Conlon, C., Beck, K. L., Kruger, M. C., & Von Hurst, P. R. (2016). Vitamin D and autism spectrum disorder: a literature review. Nutrients, 8(4), 236. https://doi.org/10.3390/nu8040236
55. Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child & Adolescent Psychiatry, 47(8), 921-929. https://doi.org/10.1097/CHI.0b013e318179964f
56. do Nascimento, P. K. D. S. B., Oliveira Silva, D. F., de Morais, T. L. S. A., & de Rezende, A. A. (2023). Zinc status and autism spectrum disorder in children and adolescents: a systematic review. Nutrients, 15(16), 3663. https://doi.org/10.3390/nu15163663
57. El-Rashidy, O., El-Baz, F., El-Gendy, Y., Khalaf, R., Reda, D., & Saad, K. (2017). Ketogenic diet versus gluten free casein free diet in autistic children: a case-control study. Metabolic brain disease, 32(6), 1935-1941. https://doi.org/10.1007/s11011-017-0088-z
58. Parletta, N., Niyonsenga, T., & Duff, J. (2016). Omega-3 and omega-6 polyunsaturated fatty acid levels and correlations with symptoms in children with attention deficit hyperactivity disorder, autistic spectrum disorder and typically developing controls. PLoS One, 11(5), e0156432. https://doi.org/10.1371/journal.pone.0156432
59. Yui, K., Koshiba, M., Nakamura, S., & Kobayashi, Y. (2012). Effects of large doses of arachidonic acid added to docosahexaenoic acid on social impairment in individuals with autism spectrum disorders: A double-blind, placebo-controlled, randomized trial. Journal of Clinical Psychopharmacology, 32(2), 200–206. https://doi.org/10.1097/JCP.0b013e3182485791
60. Brigandi, S. A., Shao, H., Qian, S. Y., Shen, Y., Wu, B. L., & Kang, J. X. (2015). Autistic children exhibit decreased levels of essential fatty acids in red blood cells. International journal of molecular sciences, 16(5), 10061-10076. https://doi.org/10.3390/ijms160510061
61. Veselinović, A., Petrović, S., Žikić, V., Subotić, M., Jakovljević, V., Jeremić, N., & Vučić, V. (2021). Neuroinflammation in autism and supplementation based on omega-3 polyunsaturated fatty acids: A narrative review. Medicina, 57(9), 893. https://doi.org/10.3390/medicina57090893
62. Berni, M., Mutti, G., Tancredi, R., Muratori, F., & Calderoni, S. (2026). Vitamin D and Omega-3 Supplementation for Emotional and Behavioral Dysregulation in Autism Spectrum Disorders: A Systematic Review. Journal of Clinical Medicine, 15(2), 745. https://doi.org/10.3390/jcm15020745
63. Nogueira-de-Almeida, C. A., de Araújo, L. A., Ued, F. da V., Contini, A. A., Nogueira-de-Almeida, M. E., Martinez, E. Z., & Fisberg, M. (2025). Nutritional factors and therapeutic interventions in autism spectrum disorder: A narrative review. Children, 12(2), 202. https://doi.org/10.3390/children12020202
64. Dhanasekara, C. S., Ancona, D., Cortes, L., Hu, A., Rimu, A. H., Robohm-Leavitt, C., & Kahathuduwa, C. N. (2023). Association between autism spectrum disorders and cardiometabolic diseases: A systematic review and meta-analysis. JAMA Pediatrics, 177(3), 248–257. https://doi.org/10.1001/jamapediatrics.2022.5629
65. Hsiao, E. Y. (2014). Gastrointestinal issues in autism spectrum disorder. Harvard review of psychiatry, 22(2), 104-111. https://doi.org/10.1097/HRP.0000000000000029
66. López‐Gil, J. F., Smith, L., Tully, M. A., Álvarez‐Pitti, J., Gómez, S. F., & Schröder, H. (2025). Prevalence of daily family meals among children and adolescents from 43 countries. Maternal & Child Nutrition, 21(1), e13706. https://doi.org/10.1111/mcn.13706
67. Seiverling, L., Williams, K., Sturmey, P., & Hart, S. (2012). Effects of behavioral skills training on parental treatment of children's food selectivity. Journal of applied behavior analysis, 45(1), 197-203. https://doi.org/10.1901/jaba.2012.45-197
68. Salari, N., Heidarian, P., Tarrahi, M. J., Mansourian, M., Canbary, Z., Daneshkhah, A., & Mohammadi, M. (2025). Global prevalence of eating disorders in children: A comprehensive systematic review and meta-analysis. Italian Journal of Pediatrics, 51(1), 107. https://doi.org/10.1186/s13052-025-01958-0
69. Sharp, W. G., Volkert, V. M., Scahill, L., McCracken, C. E., & McElhanon, B. (2017). A systematic review and meta-analysis of intensive multidisciplinary intervention for pediatric feeding disorders: how standard is the standard of care? The Journal of pediatrics, 181, 116-124. https://doi.org/10.1016/j.jpeds.2016.10.002
70. Strickland, E. (2009). Eating for autism: The 10-step nutrition plan to help treat your child's autism, Asperger's, or ADHD. Balance.
71. National Academies of Sciences, Engineering, and Medicine. (2023). Dietary reference intakes for energy. https://doi.org/10.17226/26818
72. Gernsbacher, M. A., Morson, E. M., & Grace, E. J. (2016). Language and speech in autism. Annual review of linguistics, 2, 413-425. https://doi.org/10.1146/annurev-linguistics-030514-124824
73. Dawson, G., Rogers, S., Munson, J., Smith, M., Winter, J., Greenson, J., & Varley, J. (2010). Randomized, controlled trial of an intervention for toddlers with autism: The Early Start Denver Model. Pediatrics, 125(1), e17–e23. https://doi.org/10.1542/peds.2009-0958
74. Cho, J. M., & Shin, J. W. (2025). Nutrigenomics for Autism Spectrum Disorder: A Multidisciplinary Framework for Personalized Nutrition in Special Education. Clinical Nutrition Research, 14(4), 329. https://doi.org/10.7762/cnr.2025.14.4.329








